By Gert Lubec
A new promising animal version of DS is stated and this opens new possibilities to check pathomechanisms and pharmacological methods because it is greater than tough to hold out experiences in people and the scientific gains are hugely variable. when it comes to biology, phone cycle and stem mobilephone reports and by way of biochemistry, relevance of stories on a selected protein kinase, channels, transporters, superoxide dismutase, antioxidant method, chromosome meeting issue and different vital organic buildings are supplied. And back, the gene dosage speculation is addressed and even supposing the majority of chromosome 21 gene items is unchanged in fetal DS mind, a couple of particular chromosome 21 encoded buildings together with transcription components are certainly overexpressed even though findings in fetal DS are varied from these in grownup DS mind while Alzheimer-like neuropathology supervenes.
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Advances in Down Syndrome Research (Journal of Neural Transmission. Supplementa) by Gert Lubec